Comprehensive Viral Immunology of Multiple Sclerosis
نویسنده
چکیده
0 EpldMldagkal, clinkal, and CSF data were collected on 87 patlenb wlth clinically definite multlple scleroris (MS) and 50 with probable MS. As part of a study of immundogk reactivity to vlral antigens, a control group separated into 26 patients with probable inflammatory neural disease and 140 with noninflammatory neural disease was similarly stub id. Among the groups with MS, females predominated and both Oriental and Spanish surnamed patients were underrepresented. The spinal cord, optic nerves, and brainstem were the mort common rites of initial disease and more than 20% of the patients had only cord symptoms alter several years of dlsease activity. Of several CSF assays used, determination of oligoclonal IgG band. by agarose electrophoresis WM most useful diagnostically. (Arch NeurOl37:537-541,1980)
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